| Date | Game | Time | Watch Here |
| Sunday Sep. 13 | Buffalo Bills vs New York Jets | 1:00pm ET | Watch Live |
| Sunday Sep. 20 | Buffalo Bills vs Miami Dolphins | 1:00pm ET | Watch Live |
| Sunday Sep. 27 | Buffalo Bills vs Los Angeles Rams | 1:00pm ET | Watch Live |
| Sunday Oct. 4 | Buffalo Bills vs Las Vegas Raiders | 4:25pm ET | Watch Live |
| Sunday Oct. 11 | Buffalo Bills vs Tennessee Titans | 1:00pm ET | Watch Live |
| Thursday Oct. 15 | Buffalo Bills vs Kansas City Chiefs | 8:20pm ET | Watch Live |
| Sunday Oct. 25 | Buffalo Bills vs New York Jets | 1:00pm ET | Watch Live |
| Sunday Nov. 1 | Buffalo Bills vs New England Patriots | 1:00pm ET | Watch Live |
| Sunday Nov. 8 | Buffalo Bills vs Seattle Seahawks | 1:00pm ET | Watch Live |
| Sunday Nov. 15 | Buffalo Bills vs Arizona Cardinals | 4:05pm ET | Watch Live |
| Sunday Nov. 29 | Buffalo Bills vs Los Angeles Chargers | 1:00pm ET | Watch Live |
| Monday Dec. 7 | Buffalo Bills vs San Francisco 49ers | 8:15pm ET | Watch Live |
| Sunday Dec. 13 | Buffalo Bills vs Pittsburgh Steelers | 8:20pm ET | Watch Live |
| Sunday Dec. 20 | Buffalo Bills vs Denver Broncos | Time TBA ET | Watch Live |
| Monday Dec. 28 | Buffalo Bills vs New England Patriots | 8:15pm ET | Watch Live |
| Sunday Jan. 3 | Buffalo Bills vs Miami Dolphins | 1:00pm ET | Watch Live |